Welcome to the LPS Founded to elevate the standards and qualifications of physicians engaged in the practice of pathology in Louisiana. Pathology News P46Shc inhibits mitochondrial ACAA2 thiolase, exacerbating mitochondrial injury and inflammation in aging liversAblation of Hepatic Asah1 Gene Disrupts Hepatic Lipid Homeostasis and Promotes Fibrotic Nonalcoholic Steatohepatitis in MiceGut Microbiome and Bile Acid Interactions: Mechanistic Implications for Cholangiocarcinoma Development, Immune Resistance, and TherapyCholangiocarcinoma Targeted Therapies: Mechanisms of Action and ResistanceGenetically Engineered Mouse Models for Alzheimer’s disease and Frontotemporal dementia: new insights from single-cell and spatial transcriptomics